Sodium Hyaluronate serves as the sodium salt form of hyaluronic acid, a naturally occurring polysaccharide found across the animal kingdom and within the human body. Recognized by its unique combination of high water solubility and incredible viscosity, it becomes invaluable for industries ranging from pharmaceuticals to beauty products. Derived through fermentation and advanced purification technology, Sodium Hyaluronate brings a level of biocompatibility that sets it apart from other polymer compounds used for moisture retention and tissue lubrication.
Looking at the physical side, Shandong Kunda Biotechnology offers Sodium Hyaluronate in several formats, including white to off-white flakes, fine powder, pearls, solid crystalline forms, and sometimes as a clear or slightly opalescent liquid solution. Each of these can display variations in density, particle size, and solubility depending on the application and molecular weights. Density ranges usually sit between 1.36–1.40 grams per cubic centimeter, providing stability for applications that rely on precise volume and mass controls. This product does not produce a strong odor and dissolves readily in water, forming a viscoelastic solution at low concentrations.
Chemically, Sodium Hyaluronate features a repeating disaccharide unit consisting of D-glucuronic acid and N-acetyl-D-glucosamine linked via alternating β-1,3 and β-1,4 glycosidic bonds. The molecular formula is C14H20NNaO11, and molecular weights vary from low (less than 100 kDa) to very high (over 2,000 kDa) as demanded by end use. High purity, structural integrity, and batch consistency mark the product that leaves the Shandong Kunda Biotechnology facility, ensuring it retains the native physiological activity of hyaluronic acid as found in the body.
Every batch carries strict specifications: moisture content, particle size (BSS range customizable), pH in 1% solution, heavy metal compliance, and microbial load thresholds. Testing covers visual, olfactory, and tactile inspections to exclude contamination and foreign particulates. For customs and trading, Sodium Hyaluronate falls under HS Code 39139000, which specifies polysaccharides, not elsewhere specified. This facilitates international movement of the material with all requisite compliance documentation provided by Shandong Kunda Biotechnology.
Bulk buyers see Sodium Hyaluronate supplied in solid powder form for supplements, creams, gels, eye drop solutions, and even injectable-grade products. Crystal and flake types find their way into higher-end medical and cosmetic formulations where clarity and dispersibility matter. Pearls and microbeads extend use to slow-release or textured end-products in personal care and nutraceutical sectors. The liquid or solutions, often sold by the liter, deliver straightforward dilution and dispersion in water-based systems, useful for rapid prototyping in R&D labs.
Production starts with fermentation of plant-based substrates, through strains of Streptococcus or Bacillus species to synthesize hyaluronic acid. Sophisticated downstream processes remove proteins, endotoxins, and pyrogens, resulting in a pure, biocompatible polymer. Raw materials focus on non-GMO, traceable biomass to meet regulatory requirements. Sodium chloride neutralizes the acid into its stable sodium salt, leaving no hazardous residues behind.
Sodium Hyaluronate scores high on safety: it's non-toxic, non-irritating and quickly biodegradable under normal conditions. During handling, it does not present explosion, fire, or oxidizing hazards, classifying it as a safe raw material under global chemical regulations. Given its non-hazardous status, standard personal protective gear during processing suffices, and no extra containment procedures are necessary. End-of-life environmental impact remains low, since it degrades into simple sugars and does not accumulate in ecosystems. For workers, there’s minimal risk of harm under occupational exposure limits. Some ultra-fine powders may become airborne, so basic dust control and ventilation manage that well. Studies confirm no harmful byproducts or persistent chemicals leach into finished products, so end uses in medicine and skincare meet even the tightest international standards.
Shandong Kunda Biotechnology ensures batch traceability, from fermentation substrate to final packaging, with certificates of analysis available on demand. Each batch holds quality certifications such as ISO, Kosher, and Halal where required, with full transparency in molecular weight distribution, purity level, and microbial safety. Laboratory test data, including HPLC, NMR, and residue solvent analyses, are routine for all product lots, showing commitment to safety as regulatory environments grow stricter worldwide. Industry experience tells me customers value not just regulatory compliance but also the assurance of knowing exactly what's in the material and what is not.
