Product Name: Vitamin B12 (Cyanocobalamin)
Manufacturer: Shandong Kunda Biotechnology Co., Ltd.
Chemical Formula: C63H88CoN14O14P
Synonyms: Cyanocobalamin, Cobalamin, Vitamin B12
Product Use: Food supplement, feed additive, pharmaceutical ingredient
Contact Information: Shandong Kunda Biotechnology Co., Ltd., Economic Development Zone, Shandong, China
Telephone: +86 (XXX) XXXX XXXX
Email: info@kunda.com.cn
Hazard Class: Not classified as hazardous under GHS
Main Hazards: Fine powder may cause dust; inhalation can irritate mucous membranes; high exposure can trigger mild allergic reactions; dust may present a mild explosion risk in confined areas
Pictogram: No GHS pictogram
Signal Word: None required
Precautionary Statements: Avoid inhaling dust; handle in a well-ventilated area; prevent contact with eyes and skin
Unusual Risks: May form combustible dust concentrations in air; spills can make floors slippery and hazardous
Chemical Name: Cyanocobalamin
CAS Number: 68-19-9
Concentration: ≥98% (pure forms; can be diluted in preparations)
Impurities/Additives: None significant in technical or pharma-grade material; check specific blend information for trace compounds in formulated products
Other Ingredients: May contain stabilizers or flow agents if noted on packaging or COA
Inhalation: Move individual to fresh air; seek medical attention if symptoms develop such as coughing or shortness of breath
Skin Contact: Wash with soap and water; remove contaminated clothing
Eye Contact: Rinse immediately with plenty of water (at least 15 minutes); if irritation persists, seek medical care
Ingestion: Rinse out mouth with water; drink water to dilute, but do not induce vomiting unless directed by medical personnel; contact physician if large amount swallowed
Most Important Symptoms: Not acutely toxic; dust may cause irritation or rare allergic reactions; prolonged exposure can lead to mild gastrointestinal upset
Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Unsuitable Media: High-pressure water jets, which may spread powder
Combustion Products: Carbon oxides, nitrogen oxides, cobalt oxides, phosphorus oxides, hydrocyanic acid (incomplete combustion)
Protective Equipment: Self-contained breathing apparatus, full protective gear
Special Hazards: Fine particles may form explosive dust-air mixtures; always control static discharge and ignition sources
Firefighting Instructions: Keep containers cool with water spray; avoid breathing fumes and run-off water
Personal Precautions: Use personal protective equipment, avoid dust formation, remove all ignition sources, ventilate area
Environmental Precautions: Keep out of drains, sewers, and waterways; avoid contamination of soil
Containment Methods: Sweep up and place in suitable containers for disposal; minimize dust generation
Cleanup Procedures: Wipe up residues with damp cloth; wash affected surfaces to prevent slippery conditions
Safe Handling: Minimize dust; handle in areas with local exhaust or general ventilation; ground equipment for static dissipation; avoid eating, drinking, or smoking when handling
Storage Conditions: Store in a tightly closed container in a dry, cool, well-ventilated place; protect from light, moisture, and heat
Incompatible Materials: Strong oxidizers, reducing agents, acids, alkalis
Special Arrangements: Label storage area, store away from food and animal feed
Hygiene Measures: Wash hands and exposed skin after handling, change contaminated clothing
Technical Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to control dust
Occupational Exposure Limits: No established OELs for cyanocobalamin; keep airborne dust as low as reasonably achievable
Personal Protective Equipment:
- Eye Protection: Safety goggles
- Skin Protection: Lab coat, gloves (nitrile or vinyl recommended)
- Respiratory Protection: Dust mask (N95 or higher) during powder handling
- Hygiene: Wash hands before meals and after use; remove contaminated clothing and wash before reuse
Environmental Controls: Avoid release to the environment by using closed systems for manufacturing or blending
Appearance: Dark red to reddish-brown crystalline powder
Odor: Odorless or faint characteristic odor
Odor Threshold: Not available
pH: 4.0–7.0 (1% solution)
Melting Point: Decomposes above 230°C (does not melt readily)
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, sparingly soluble in alcohol
Density: ~1.2–1.4 g/cm³
Partition Coefficient (log Kow): Not available
Vapor Pressure: Negligible
Viscosity: Not applicable
Flash Point: Not relevant (solid, non-flammable in normal use)
Explosive Properties: Powder may form explosive dust-air mixtures in rare cases
Oxidizing Properties: No significant oxidizing properties noted
Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions under normal conditions
Possible Hazardous Reactions: Contact with strong oxidizers or reducing agents can cause decomposition
Conditions to Avoid: Heat, moisture, direct sunlight, sources of ignition
Incompatible Materials: Oxidizing agents, acids, alkalis, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, cobalt oxides, hydrocyanic acid in fire conditions
Acute Toxicity: Low acute oral toxicity (LD50 oral-rat: >5000 mg/kg); virtually non-toxic in standard use
Skin Corrosion/Irritation: Not irritating to skin in usual handling
Eye Damage/Irritation: May cause mild eye irritation from dust
Respiratory Sensitization: Prolonged inhalation of dust can irritate respiratory tract
Germ Cell Mutagenicity: Not genotoxic in recognized in vivo or in vitro studies
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of harmful reproductive effects
Repeated Dose Toxicity: No known chronic toxicity in reasonable, regulated exposure
Additional Information: Overdose through ingestion may cause mild gastrointestinal upset
Ecotoxicity: Not considered acutely toxic to aquatic life
Mobility in Soil: Expected to be low, but water solubility may allow local movement
Persistence and Degradability: Biodegradable under environmental conditions
Bioaccumulative Potential: Not expected to bioaccumulate or persist in the food chain
Other Adverse Effects: No known environmental hazards with responsible use
Waste Treatment Methods: Collect material in appropriate containers; dispose of in compliance with local, regional, and national regulations
Contaminated Packaging: Triple rinse containers, recycle or dispose according to regulations
Special Precautions: Do not discharge to drains or water courses; landfill or incineration with proper authorization
Recommended Disposal: Render inactive by dilution and dispose through trained professional waste management if volume exceeds minor laboratory quantities
UN Number: Not classified as dangerous goods under UN recommendations
Proper Shipping Name: Vitamin B12, Cyanocobalamin
Hazard Class: Not hazardous for transport
Packing Group: Not applicable
Environmental Hazards: None
Special Precautions for User: Protect from moisture and breakage; secure containers to prevent leaks
Transport Labels: No special labeling required
Regulation Status: Not regulated as a hazardous substance under major chemical safety regulations
Safety, Health, and Environmental Regulations: Subject to REACH (EU) registration in Europe; TSCA inventory in the USA; regulated as a food additive in food and feed sectors
Workplace Regulation: General dust and chemical hygiene standards apply
Labeling Requirements: Follow workplace labeling guidelines
SDS Availability: SDS should be made available to users at the point of handling and storage; staff training on hazards and precautions advised
