Product Name: Vitamin A
CAS Number: 68-26-8
Manufacturer: Shandong Kunda Biotechnology Co., Ltd.
SDS Number: KDVIT-A-001
Recommended Use: Feed additive, dietary supplement, fortification of foodstuffs
Address: Qufu High-tech Industrial Development Zone, Shandong Province, China
Emergency Phone: +86-537-1234567
Email: safety@kundabiotech.com
Classification: Acute oral toxicity (Category 3), Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity – single exposure (Category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation at high concentration, possible harmful effects from prolonged exposure
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Wash hands thoroughly after handling, avoid breathing dust, use protective gloves and eye protection, do not eat or drink during use, in case of inadequate ventilation, wear respiratory protection
Main Ingredient: Vitamin A acetate or palmitate
Chemical Formula: C22H32O2 (retinyl acetate), C36H60O2 (retinyl palmitate)
Concentration: 99% or as specified in batch specification
Other Components: Carriers such as starch, gelatin, sucrose, or antioxidants; none present in hazardous quantities
Impurities or Stabilizers: Less than 1%, generally not classified as hazardous
Inhalation: Move affected individual to fresh air, loosen clothing, seek medical advice if symptoms such as coughing or shortness of breath occur
Skin Contact: Remove contaminated clothing, wash skin with plenty of soap and water for 15 minutes, consult a physician in case of persistent irritation
Eye Contact: Rinse immediately with gentle stream of water for at least 15 minutes, remove contact lenses if possible, seek medical attention if irritation persists
Ingestion: Rinse mouth, give water to drink if conscious, never give anything by mouth to an unconscious person, consult medical team or poison center if large quantities swallowed
Notes to Physician: Treat symptoms, no specific antidote, monitor liver and kidney function if substantial ingestion suspected
Suitable Extinguishing Media: Use water spray, foam, carbon dioxide, or dry chemical; large fires may require alcohol-resistant foam
Specific Hazards: Dust may form explosive mixture with air, combustion may release harmful fumes such as carbon monoxide, carbon dioxide, and acrid smoke
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Avoid breathing fumes, cool drums or containers with water spray to prevent pressure build-up, evacuate area if necessary
Personal Precautions: Evacuate unnecessary personnel, use suitable personal protective equipment including gloves, goggles, and dust mask, ventilate area, avoid dust generation
Environmental Precautions: Prevent product from entering drains, sewers, or watercourses
Methods for Containment: Gently collect and scoop spilled material to avoid creating dust, place in suitable labelled containers for recovery or disposal
Cleanup Methods: After removal, wash area with water and detergent, dispose of washings in accordance with local regulations, ventilate area thoroughly
Safe Handling: Keep container tightly closed, minimize dust generation and accumulation, avoid contact with skin and eyes, do not eat, drink or smoke while handling, use only in well-ventilated areas
Hygiene Measures: Remove contaminated clothing, wash hands and face after handling material
Storage Conditions: Store in original container in cool, dry, well-ventilated place, away from heat sources or combustion, protect from light and moisture, do not store with incompatible substances such as oxidizers
Packaging Materials: Use containers made of polyethylene, glass, or coated steel to avoid reaction with Vitamin A
Occupational Exposure Limits: No specific countrywide exposure limit for Vitamin A, recommended threshold is 10 mg/m3 (total dust)
Engineering Controls: Ensure adequate ventilation, use local exhaust system where dust is generated
Personal Protection: Respiratory protection with dust mask or respirator if airborne concentration exceeds threshold, protective gloves (nitrile, latex), safety goggles or face shield, protective clothing to prevent skin contact
Environmental Exposure Controls: Avoid release into environment, regular cleaning of area, use closed systems where feasible
Appearance: Yellow to orange crystalline powder or oily liquid (depending on formulation)
Odor: None or faint, characteristic
Odor Threshold: Not applicable
pH: Not applicable in solid form; slightly acidic if dissolved
Melting Point: 28°C for retinyl palmitate, 57°C for retinyl acetate
Boiling Point: Decomposes before boiling
Flash Point: >110°C (closed cup)
Evaporation Rate: Not applicable
Flammability: May form combustible dust–air mixtures
Upper/Lower Flammability Limit: Not determined
Vapor Pressure: Very low at room temperature
Relative Density: Approximately 0.94–1.01 g/cm³
Solubility: Insoluble in water, soluble in fats, oils, and some organic solvents
Partition Coefficient (n-octanol/water): Log Pow ~6.5
Decomposition Temperature: >180°C
Viscosity: Not determined
Chemical Stability: Stable when stored under recommended conditions, sensitive to air, light, and heat
Reactivity: Reacts with strong oxidizing agents, acids and alkalis
Hazardous Decomposition Products: May form carbon monoxide, carbon dioxide, and other toxic vapors during combustion or thermal decomposition
Conditions to Avoid: Heat, moisture, direct sunlight, sources of ignition, static discharge
Polymerization: Not known to occur
Acute Toxicity: Oral LD50 (rat) ~2,000 mg/kg; excessive intake may lead to headache, dizziness, nausea, vomiting, dry skin, and other symptoms of hypervitaminosis A
Skin Corrosion/Irritation: Mild irritant to skin
Eye Damage/Irritation: Irritating to eyes, may cause redness, tearing, and temporary vision effects
Respiratory Sensitization: Large amounts or high concentration of dust may cause respiratory tract irritation
Chronic Effects: Prolonged or repeated ingestion can harm liver and cause symptoms such as jaundice, birth defects in pregnant women, bone pain
Carcinogenicity: Not classified as carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity: No evidence from animal studies of genetic toxicity
Reproductive Toxicity: High doses may be teratogenic in pregnancy
Toxicity to Fish: LC50 (96 hour, fathead minnow): >10 mg/L; low aquatic toxicity at typical concentrations
Persistence and Degradability: Readily biodegradable under aerobic conditions, photo-degrades in sunlight
Bioaccumulative Potential: High potential due to fat solubility (log Pow >6)
Mobility in Soil: Low mobility; will adsorb to soil and sediments
Other Adverse Effects: No known effects on wastewater treatment bacteria, limit release into natural waterways to avoid long-term accumulation
Waste Treatment Methods: Dispose of as non-hazardous organic waste in accordance with national and local regulations, incineration in authorized plant preferred, avoid landfilling large quantities
Container Disposal: Rinse empty package thoroughly, scrap to recovery or controlled landfill if allowed locally, do not reuse packaging for food or feed purposes
Precautions: Prevent dust generation, use personal protective equipment during waste handling, keep material out of water sources
UN Number: Not regulated as dangerous goods by ADR, IMDG, or IATA
Proper Shipping Name: Vitamin A or Nutritional supplement
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not a marine pollutant
Special Precautions for User: Avoid contact with incompatible chemicals, protect against spillage, keep containers sealed and upright
EU Regulations: Not classified as hazardous under CLP Regulation (EC) No 1272/2008, inventories: EINECS, REACH registered
US Regulations: Listed on TSCA inventory, FDA-approved for food and feed use, not regulated by OSHA as hazardous
Other Regulations: Complies with GB standards for feed additives, registered with Chinese Ministry of Agriculture
Labelling Requirements: Follow guidance for chemical labeling, include risk and safety statements
