Material Safety Data Sheet for Shandong Kunda Biotechnology Sodium Hyaluronate

Identification

Product Name: Sodium Hyaluronate
Manufacturer: Shandong Kunda Biotechnology Co., Ltd.
Recommended Uses: Personal care products, pharmaceutical ingredients, food additives
Contact Information: Shandong Kunda Biotechnology, New & High Industry Park, Qufu, Shandong, China
Emergency Phone: +86-537-4567890
Email: info@kundabio.com

Hazard Identification

Classification: Non-hazardous substance according to international standards
Main Hazards: Fine dust can cause mild respiratory irritation to some individuals. Contact with eyes may trigger temporary discomfort. No known chronic health effects from standard exposure.
Label Elements: No pictogram, signal word not required, hazard statements: None
Precautionary Statements: Prevent dust accumulation, avoid breathing dust, wash hands after handling, avoid contact with eyes and open wounds

Composition / Information on Ingredients

Chemical Name: Sodium Hyaluronate
Common Synonyms: Hyaluronic Acid Sodium Salt
CAS Number: 9067-32-7
Molecular Formula: (C14H20NNaO11)n
Content: 95% minimum purity
Impurities: Water < 5%, trace residual protein, no added preservatives or stabilizers

First Aid Measures

Inhalation: Move person to fresh air, seek medical help if symptoms develop or persist
Skin Contact: Rinse with soap and plenty of water, remove contaminated clothing, contact physician if irritation continues
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, call for medical help if irritation does not subside
Ingestion: Rinse mouth with water, drink water to dilute, seek medical attention for discomfort or persistent symptoms

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide
Specific Hazards Arising: Product is not flammable, decomposition under fire can produce carbon oxides and trace nitrogen oxides
Protective Equipment for Firefighters: Wear full protective gear, self-contained breathing apparatus is recommended for major fires
Advice for Firefighters: Control running water from hose streams to prevent spread of material, avoid inhaling smoke or combustion gases

Accidental Release Measures

Personal Precautions: Avoid dust formation, ventilate area, wear appropriate respirator if excessive dust is generated
Environmental Precautions: Prevent entry into water systems and sewers, scoop or vacuum up material
Methods for Cleanup: Collect by moistening powder to reduce dust, place in containers for disposal, wipe affected surfaces with damp cloth, dispose according to local regulations

Handling and Storage

Handling: Work in well-ventilated space, use equipment to keep dust low, practice good industrial hygiene, wear suitable gloves and goggles if exposure expected
Storage: Store at room temperature in tightly closed original packaging, keep away from moisture, direct sunlight, strong acids and bases, and oxidizing agents
Specific End Use: Follow industry safety guidelines for cosmetic or pharmaceutical utilization, keep containers labeled and sealed

Exposure Controls and Personal Protection

Exposure Limits: No occupational limit established; follow general dust exposure guidelines (OSHA/ACGIH: 10 mg/m³ total, 3 mg/m³ respirable)
Engineering Controls: Local exhaust or ventilation recommended, install dust collection system for large-scale processing
Personal Protective Equipment: Gloves: standard nitrile or latex; Respiratory: dust mask or respirator if airborne concentration exceeds safe levels; Eye Protection: safety goggles or glasses if risk of dust noted; Hygiene: wash hands after contact, avoid eating or drinking during handling

Physical and Chemical Properties

Appearance: White to off-white, odorless powder
Odor: Neutral, no strong scent
pH: 6.0–8.0 (0.1% in water solution)
Melting Point: Not applicable (decomposes before melting)
Boiling Point: Not applicable
Flash Point: Not flammable under normal conditions
Solubility: Fully soluble in water, forms a clear viscous solution
Bulk Density: ~0.2–0.4 g/cm³
Viscosity: High viscosity solutions at low concentrations
Other Data: No explosive or oxidizing properties; stable under normal conditions of storage and use

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive with common chemicals under normal use
Hazardous Reactions: No known risk of hazardous reactions
Conditions to Avoid: Avoid strong acids, strong bases, oxidizing agents, elevated humidity and temperature extremes
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides (under fire or intense heat)

Toxicological Information

Acute Toxicity: Oral and dermal routes show low toxicity in animal studies
Skin Corrosion/Irritation: Not expected to irritate intact skin, minor irritation possible for sensitive individuals
Eye Damage/Irritation: Risk of mild, reversible irritation if exposed
Respiratory Sensitization: Dust can cause coughing or dryness for sensitive groups
Carcinogenicity: Not listed by IARC, NTP, OSHA
Other Information: Long-term exposure studies do not indicate risk of chronic effects or sensitization; used in pharmaceutical and cosmetic applications worldwide

Ecological Information

Ecotoxicity: Product shows low ecological risk; sodium hyaluronate is biodegradable
Persistence and Degradability: Rapidly decomposes in environmental conditions
Bioaccumulation Potential: No tendency to bioaccumulate
Mobility in Soil: High solubility in water promotes dispersion and rapid degradation
Other Adverse Effects: No specific hazards for aquatic or terrestrial life when spills controlled and proper disposal standards upheld

Disposal Considerations

Waste Handling Methods: Dispose of as non-hazardous solid waste according to local regulation
Packaging Disposal: Empty containers should be rinsed and recycled or disposed of in line with regional guidelines
Environmental Precautions: Do not release large concentrations into sewage or aquatic systems
Other Notes: Encourage usage of entire content before packaging disposal to minimize waste

Transport Information

UN Number: Not classified as dangerous goods for transport
Proper Shipping Name: Sodium Hyaluronate
Transport Hazard Class: Not regulated
Packing Group: None
Environmental Hazards: Not a marine pollutant or hazardous for road, rail, air, or sea transport
Special Precautions: Keep product dry and sealed through transit, handle cartons carefully to prevent puncture or spillage

Regulatory Information

National/International Regulation: Meets global cosmetic and pharmaceutical ingredient safety requirements
Inventory Listing: China IECSC, US TSCA, EU EINECS/REACH, Japan ENCS
SDS Compliance: Prepared in accordance with Globally Harmonized System (GHS)
Other Regulation: Not subject to any specific restrictions, not classified as controlled or scheduled substance
Workplace Labeling: Appropriate risk phrases and handling instructions should be displayed in work areas