Material Safety Data Sheet (MSDS): Shandong Kunda Biotechnology Pyridoxine Hydrochloride

Identification

Product Name: Pyridoxine Hydrochloride
Supplier/Manufacturer: Shandong Kunda Biotechnology Co., Ltd.
Chemical Formula: C8H11NO3·HCl
CAS Number: 58-56-0
Synonyms: Vitamin B6, Pyridoxol Hydrochloride
Intended Use: Food additive, pharmaceutical ingredient, animal feed additive
Contact Information: Shandong Kunda Biotechnology, Industrial Park, Yanzhou District, Jining City, Shandong Province, China
Emergency Contact Number: +86-xxx-xxxxxxx (direct line to company safety officer)

Hazard Identification

Classification: Non-flammable, non-explosive
GHS Classification: Not classified as hazardous under GHS regulation
Potential Health Effects: Inhalation may cause mild respiratory irritation; ingestion in large amounts can lead to gastrointestinal discomfort; possible skin and eye irritation
Label Elements: No pictograms required
Signal Word: None
Precautionary Statement: Avoid unnecessary dust generation; use appropriate personal protective equipment
Hazard Statement: Low acute toxicity, not expected to pose significant health risk in normal use
Other Hazards: No known significant environmental hazards or chronic health risks

Composition / Information on Ingredients

Chemical Name: Pyridoxine Hydrochloride
Chemical Formula: C8H11NO3·HCl
CAS Number: 58-56-0
Concentration: ≥ 99% Pyridoxine Hydrochloride
Impurities: Trace residual solvents below regulatory thresholds; water content < 0.5%
Other Components: No hazardous additives or non-disclosed ingredients

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if respiratory discomfort persists
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and continue rinsing
Ingestion: Rinse mouth; obtain medical advice if large quantities consumed or if irritation occurs
Most Important Symptoms: Mild respiratory irritation, possible skin or eye redness; not known to trigger severe or lasting symptoms under routine exposure
Special Note to Physician: Symptomatic treatment as needed

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: No media restrictions, but full water jet may scatter powder
Hazards from Combustion: Emits nitrogen oxides and hydrochloric acid fumes at high temperature
Protective Equipment for Firefighters: Positive pressure self-contained breathing apparatus, protective gloves, fire-resistant clothing
Firefighting Procedures: Move containers from area if safe; cool adjacent containers with water spray
Special Precautions: Avoid dust inhalation and contact with eyes during fire response

Accidental Release Measures

Personal Protection: Use respiratory protection for airborne dust, nitrile gloves, chemical safety goggles
Environmental Precautions: Prevent spills from entering drains, natural waters, or soil
Spill Clean-Up Methods: Sweep up carefully; avoid dust generation; collect in suitable container for disposal; ventilate area
Decontamination: Wash spill area with water and mild detergent after removal
Disposal Considerations: Label and handle sweepings as chemical waste

Handling and Storage

Safe Handling Recommendations: Avoid contact with skin and eyes; prevent inhalation of dust; wear proper PPE
Hygiene Measures: Wash hands and exposed skin after handling and before eating
Storage Conditions: Store in tightly closed, original container at room temperature; keep out of direct sunlight; store in dry, well-ventilated area
Incompatible Materials: Strong oxidizing agents
Storage Stability: Stable under recommended storage conditions; protect from moisture and contamination

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits established
Ventilation: Use local exhaust or general room ventilation as required
Personal Protection: Approved dust mask or respirator, protective gloves, chemical goggles, lab coat or overalls
Hygiene Practices: Do not eat, drink, or smoke in work area; wash hands after handling
Environmental Controls: Use procedures and equipment to prevent dust release into air or water systems

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
pH: 2.3–3.5 (5% aqueous solution)
Melting Point/Freezing Point: 204–206°C (decomposition)
Boiling Point: Not applicable (decomposes on heating)
Solubility: Soluble in water (100 mg/mL at 20°C); sparingly soluble in alcohol
Partition Coefficient (log Kow): -1.2 (estimated)
Molecular Weight: 205.64 g/mol
Vapor Pressure: Negligible at room temperature
Density: 1.1–1.3 g/cm3
Flash Point: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal temperature and recommended storage
Conditions to Avoid: High heat, moisture, strong oxidizers
Reactivity: Not reactive under intended use and storage
Hazardous Decomposition Products: Nitrogen oxides, hydrochloric acid gas, carbon monoxide, carbon dioxide on combustion
Polymerization: Will not occur

Toxicological Information

Acute Toxicity: Oral LD50 (rat) > 4000 mg/kg, low toxicity
Skin Irritation: Mild irritation possible with prolonged exposure
Eye Irritation: May cause temporary redness and discomfort
Sensitization: Not a known skin sensitizer
Chronic Effects: High chronic intake (overdose situations) linked to peripheral neuropathy (rare, at very high doses)
Carcinogenicity: Not listed as carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity: No evidence from standard tests
Reproductive Toxicity: No identified reproductive or developmental hazards at occupational exposure

Ecological Information

Environmental Fate: Readily biodegradable under aerobic conditions
Aquatic Toxicity: No acute aquatic toxicity at expected environmental concentrations
Bioaccumulation: Low bioaccumulation potential
Mobility in Soil: High solubility, may leach if large accidental spills occur
Other Adverse Effects: No significant ozone depletion potential or other long-term global effects known

Disposal Considerations

Disposal Methods: Dispose of in accordance with local, regional, and national regulations
Contaminated Packaging: Triple rinse and dispose or recycle as permitted;
Environmental Precautions: Avoid release to streams or sewers
Special Instructions: Do not incinerate with household garbage; chemical waste should go to properly licensed facility

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods
Hazard Class: Not applicable
Packing Group: Not applicable
Label: No hazard label required
Transportation Precautions: Avoid generating dust during transport; keep containers tightly sealed and dry

Regulatory Information

Inventory Status: Listed on China IECSC, United States TSCA, European Union EINECS, Japan ENCS, Korea ECL
Food and Drug Regulations: Cleared for use as food additive and pharmaceutical raw material as per national and international regulations
Waste Regulations: Non-hazardous waste under general chemical code, observe site-specific waste guidelines
Other Regulatory Notes: No restrictions or special controls under major global chemical regulations