Product Name: Niacinamide
Other Names: Nicotinamide, Vitamin B3
Manufacturer: Shandong Kunda Biotechnology Co., Ltd.
Recommended Use: Nutraceutical, Cosmetic, Pharmaceutical Ingredients
Contact Information: Shandong Kunda Biotechnology Co., Ltd., No. 198, Kunda Road, Shandong Province, China, Tel: +86-535-1234567
Emergency Contact: CHEMTREC (24h) +1-800-424-9300
Product Code: NA-001
GHS Classification: Not classified as hazardous under GHS.
Physical Hazards: Dust generation.
Health Hazards: May cause mild skin and eye irritation.
Environmental Hazards: Can affect aquatic organisms at high concentrations.
Signal Word: None required.
Pictogram: Not assigned.
Precautionary Statement: Avoid inhalation and contact with eyes or skin.
Chemical Name: Niacinamide
Synonyms: Nicotinamide
CAS Number: 98-92-0
EC Number: 202-713-4
Formula: C6H6N2O
Content: ≥ 99.5% by weight
Impurities: Water (≤0.5%), Heavy metals (≤0.001%)
Inhalation: Move to fresh air. Seek medical advice if symptoms develop.
Skin Contact: Remove contaminated clothing. Wash skin with soap and water.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and continue rinsing.
Ingestion: Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms appear.
Most Important Symptoms: Mild irritation of skin, eyes, or respiratory tract.
Medical Attention: Treat symptomatically.
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide.
Unsuitable Extinguishing Media: None known.
Specific Hazards: Combustion may release toxic fumes, including nitrogen oxides and carbon oxides.
Special Protective Equipment: Wear self-contained breathing apparatus and protective clothing.
Firefighting Instructions: Avoid inhalation of fumes. Cool containers exposed to flames with water spray.
Personal Precautions: Avoid generation of dust. Use local exhaust ventilation. Wear suitable protective equipment including gloves, goggles, and mask.
Emergency Procedures: Restrict access to area. Eliminate ignition sources.
Methods for Clean-up: Sweep up and collect in suitable container for disposal. Avoid dispersal of dust into the air. Wash area with plenty of water after removal.
Environmental Precautions: Prevent entry into waterways, drains, or soil.
Precautions for Safe Handling: Minimize dust generation and accumulation. Use in well-ventilated area. Wash hands thoroughly after use. Avoid contact with skin, eyes, and clothing.
Conditions for Safe Storage: Store in a cool, dry, well-ventilated place. Keep container tightly closed. Protect from sunlight, moisture, and incompatible substances such as strong oxidizers.
Storage Temperature: Recommended below 25°C.
Incompatible Materials: Strong oxidizing agents, acids, and bases.
Occupational Exposure Limits: No occupational exposure limit established for Niacinamide.
Engineering Controls: Use local exhaust ventilation. Provide eyewash stations and safety showers near work areas.
Personal Protective Equipment:
Appearance: White, crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 6.0 – 7.5 (5% solution)
Melting Point: 128°C – 131°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, glycerol
Vapor Pressure: Negligible at room temperature
Density: 1.40 g/cm³
Flashpoint: Not applicable
Explosive Properties: Not explosive
Oxidizing Properties: Not oxidizing
Chemical Stability: Stable under normal conditions of storage and handling.
Conditions to Avoid: High humidity, heat, direct sunlight.
Reactivity: Inert under normal temperatures and pressures.
Hazardous Reactions: None known under standard use.
Materials to Avoid: Strong oxidizing agents, acids, and bases.
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides upon burning.
Acute Toxicity: Oral LD50 (rat): > 5,000 mg/kg (low toxicity)
Skin Irritation: Not an irritant at recommended handling.
Eye Irritation: Slight irritant on direct contact.
Chronic Effects: Prolonged exposure may cause mild skin or eye irritation.
Sensitization: Not considered a sensitizer.
Mutagenicity: No evidence of mutagenic activity based on available studies.
Reproductive Toxicity: No known reproductive hazards.
Other Information: No additional known effects.
Ecotoxicity: Low toxicity to aquatic life based on OECD data.
Persistence and Degradability: Biodegradable under aerobic conditions.
Bioaccumulative Potential: No significant bioaccumulation is expected.
Mobility in Soil: High solubility in water; may leach into groundwater under large release scenarios.
Other Adverse Effects: No further data available.
Waste Treatment Methods: Dispose of according to local, regional, and national regulations.
Product Disposal: Incinerate or landfill in accordance with environmental regulations.
Container Disposal: Containers should be triple-rinsed, punctured, and disposed of in a permitted facility.
Special Precautions: Do not discharge into water bodies, sewer systems, or soil.
UN Number: Not regulated as dangerous goods.
Proper Shipping Name: Niacinamide
Transport Hazard Class: Non-hazardous for transport.
Packing Group: None assigned
Marine Pollutant: No
Special Transport Precautions: Avoid generating dust during transport. Protect from damp and contamination.
International Inventories: Listed on TSCA, EINECS, DSL/NDSL, AICS, and other major inventories.
Regulatory Status: Not classified as hazardous under OSHA, EU CLP, or GHS.
Labeling Requirements: No labeling required under international chemical control laws.
Other Regulations: Complies with food, cosmetic, and pharmaceutical ingredient guidelines where permitted.
Workplace Exposure Guidelines: General ventilation and standard industrial hygiene practices recommended.
