Product Name: Isoleucine
SYNONYMS: L-Isoleucine; 2-Amino-3-methylvaleric acid
CAS Number: 73-32-5
Supplier: Shandong Kunda Biotechnology Co., Ltd.
Address: Qufu City, Shandong Province, China
Emergency Telephone: Contact regional poison center or emergency medical assistance
Recommended Use: Amino acid for feed or food use, ingredient in supplements, research applications
Classification according to GHS: Not classified as hazardous under GHS
Label Elements: No symbol, no signal word required
Hazard Statements: No specific hazard identified based on available data
Precautionary Statements: Use appropriate safety measures, avoid dust generation, practice good housekeeping
Pictograms: None
Other Hazards: Dust generation possible; combustible in fine particulate form; may cause mild irritation upon eye or skin contact
Chemical Name: L-Isoleucine
CAS Number: 73-32-5
Molecular Formula: C6H13NO2
Molecular Weight: 131.17 g/mol
Purity: Typically above 98%
Impurities: Trace amounts of related amino acids and water; no hazardous impurities above regulatory thresholds reported
Inhalation: Move person to fresh air, seek medical attention for persistent respiratory irritation
Skin Contact: Remove contaminated clothing, wash affected area thoroughly with soap and water, consult medical professional for continued irritation
Eye Contact: Rinse eyes with water, open eyelids wide and flush gently for several minutes, contact physician if irritation continues
Ingestion: Wash out mouth thoroughly, drink water if conscious, seek medical attention for discomfort
Notes to Physician: Show this MSDS; treat symptoms and provide supportive care
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards from Fire: Fine dust may form explosive mixture with air under certain conditions; thermal decomposition may produce nitrogen oxides, carbon monoxide, carbon dioxide
Specific Protective Actions: Remove containers from fire area if safe to do so; cool with water spray to prevent pressure build-up
Protective Equipment: Wear self-contained breathing apparatus, full protective clothing during fire-fighting
Fire Residue Handling: Avoid breathing vapors, ensure proper ventilation during cleanup
Personal Precautions: Avoid contact with eyes and skin, use personal protective equipment, avoid inhalation of dust
Environmental Precautions: Prevent runoff into drains, waterways, and soil
Containment: Prevent spillage from spreading, sweep or vacuum without generating dust
Cleanup Procedures: Collect using non-sparking tools, place in appropriate labeled waste containers, dispose in accordance with local regulations
Additional Recommendations: Wash area with water after removal of bulk material; ensure good ventilation during cleanup
Handling: Minimize dust generation and accumulation, provide adequate ventilation, use personal protective equipment such as gloves and safety goggles, do not eat or drink while handling, practice good hygiene
Storage: Store in tightly closed container, keep in a cool, dry, well-ventilated place, protect from direct sunlight, incompatible with strong oxidizers, keep away from ignition sources
Special Notes: Maintain labeled containers, check containers regularly for leaks or corrosion
Exposure Limits: No occupational exposure limits defined for Isoleucine; handle as nuisance dust (ACGIH TLV for particulates not otherwise classified: 10 mg/m3 inhalable, 3 mg/m3 respirable)
Engineering Controls: Use local exhaust ventilation or process enclosure where dust is generated
Personal Protection: Eye/face protection: Safety glasses; gloves: Nitrile or PVC; clothing: Lab coat or protective clothing; respiratory: Dust mask or respirator (NIOSH approved) if handling in bulk or dusty conditions
Hygiene Measures: Always wash hands after handling, do not eat, drink, or smoke in work area, remove contaminated clothing and launder before reuse
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 5.5-7.0 (1% aqueous solution)
Melting Point: 284°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not applicable
Flammability: Not classified as flammable, but fine dust may pose explosion risk
Explosive Properties: Dust explosion possible in confined areas with air
Vapor Pressure: Not applicable
Solubility: Slightly soluble in water, practically insoluble in ethanol
Partition Coefficient (n-octanol/water): Not available
Bulk Density: 400-550 kg/m3
Viscosity: Not applicable
Decomposition Temperature: Above 284°C
Evaporation Rate: Not applicable
Stability: Stable under recommended storage and handling conditions
Reactivity: No dangerous reactions known under normal use
Possibility of Hazardous Reactions: Dust can form explosive mixture with air in confined spaces
Conditions to Avoid: Excess heat, open flames, sparks, static discharge, contact with strong oxidizers
Incompatible Materials: Strong oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, ammonia on thermal decomposition
Acute Toxicity: Oral LD50 (rat) >5000 mg/kg, indicating low acute toxicity
Skin Corrosion/Irritation: Mild irritant in sensitive individuals
Serious Eye Damage/Irritation: May cause irritation with direct contact
Respiratory Sensitization: Prolonged inhalation exposure may cause irritation to respiratory tract
Skin Sensitization: Not a known sensitizer
Germ Cell Mutagenicity: No relevant data available; not considered genotoxic
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of reproductive or developmental toxicity
STOT – Single/Repeated Exposure: No known organ toxicity with normal industrial or laboratory use
Aspiration Hazard: Not an aspiration hazard
Ecotoxicity: Not expected to be hazardous to aquatic or terrestrial organisms at normal usage concentrations; low toxicity based on amino acid structure
Persistence and Degradability: Readily biodegradable in the environment
Bioaccumulative Potential: Not expected to bioaccumulate (biological origin and rapid metabolism)
Mobility in Soil: Low mobility, slight solubility limits migration
Other Adverse Effects: No significant environmental concerns expected at industrial or commercial use levels
Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations
Unused Material: Recycle or send to approved landfill; small quantities may be washed to drain with copious amounts of water if regulations permit
Contaminated Packaging: Dispose as chemical waste; triple rinse, discard according to established guidelines
Special Precautions: Avoid creating dust during disposal; do not discharge into environment, drains, or water bodies
UN Number: Not regulated for transport
UN Proper Shipping Name: Not restricted
Transport Hazard Class: No classification required
Packing Group: Not applicable
Environmental Hazards: Not classified as environmentally hazardous
Transport Precautions: Use dry, intact containers, secure loads to avoid spillage, protect from moisture during transit
Additional Notes: Not considered dangerous for road, sea, air, or rail transport under current international transport regulations
EU Regulations: Not classified under Regulation (EC) No 1272/2008 (CLP); not listed as a hazardous substance
US Regulations: Not listed by OSHA as hazardous; not subject to SARA Title III or CERCLA reporting
Canadian Regulations: Not classified as hazardous under WHMIS 2015
Other National Inventories: Listed on EINECS, TSCA Inventory, and other chemical inventories where required
Chemical Safety Assessment: Not required for food/feed grade materials, but proper handling, storage, and disposal practices must be followed
Workplace Control: Good industrial hygiene practices should be maintained, including proper training for workers and up-to-date documentation for emergency response
