Product Name: Folic Acid
Synonyms: Vitamin B9, Pteroylglutamic acid
Manufacturer: Shandong Kunda Biotechnology Co., Ltd.
Address: Qihe Economic Development Zone, Dezhou, Shandong, China
CAS Number: 59-30-3
Recommended Use: Nutritional supplement, food additive, laboratory chemical
Contact Number for Emergency: +86-534-5643666
Email: info@kundabio.com
Hazard Classification: Not considered hazardous under normal conditions
Health Hazards: May cause mild irritation to eyes and skin, inhalation of dust can cause respiratory irritation
Environmental Hazards: No significant environmental impact under standard usage
GHS Signal Word: Not required
Pictograms: None
Precautionary Statements: Avoid generating dust, wash thoroughly after handling, use in well-ventilated areas
Potential Long-Term Effects: Chronic overexposure not documented in literature, but excessive intake may mask vitamin B12 deficiency
Chemical Name: Folic Acid
Molecular Formula: C19H19N7O6
Molecular Weight: 441.4 g/mol
Content: >98% folic acid
Impurities: Less than 2% related compounds (by-product, water, residual solvents)
Other Ingredients: None
Inhalation: Move patient to fresh air, keep at rest, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin with large amounts of water and mild soap
Eye Contact: Rinse eyes with water for at least 15 minutes, open eyelids widely and seek medical attention if irritation continues
Ingestion: Rinse mouth, drink water if alert, do not induce vomiting unless instructed by medical personnel
Symptoms: Redness, irritation, coughing, mild gastrointestinal discomfort possible
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Media: High pressure water jets in case of powder dispersal
Specific Hazards: Combustion produces carbon oxides, nitrogen oxides, and other toxic fumes
Protective Equipment: Wear self-contained breathing apparatus, full protective clothing
Advice for Firefighters: Move containers from fire area if safe; keep cool with water spray; avoid inhalation of smoke or vapors
Personal Precautions: Avoid inhalation of dust, use dust mask, gloves and goggles
Environmental Precautions: Do not let large quantities enter drains or waterways
Methods for Cleanup: Gather spilled material with non-sparking tools, sweep up and place in suitable labeled containers for disposal; ventilate area and wash spill site after pickup
Preventive Measures: Isolate area, minimize dust, avoid contact with skin and eyes
Precautions for Safe Handling: Avoid formation of dust clouds, use adequate local exhaust ventilation, do not eat, drink, or smoke during use, wash hands after handling
Storage Conditions: Store tightly closed in original container, in a cool, dry, well-ventilated room, away from sunlight and incompatible substances
Incompatible Materials: Strong oxidizing agents, acids, bases
Special Requirements: Keep away from food and animal feed, keep container labeled and secure
Specific Use: See product label for application directions; do not use for purposes not specified by supplier
Occupational Exposure Limits: No exposure limits set for folic acid; general dust limits may apply (e.g., OSHA TWA 15 mg/m3 for total dust)
Engineering Controls: Use local exhaust ventilation, process enclosure, natural or forced ventilation to control airborne particulates
Personal Protective Equipment: Safety goggles, dust mask or respirator compliant with local standards, lab coat, gloves
Hygiene Measures: Wash hands, remove soiled clothing, avoid eating or drinking near product handling
Environmental Controls: Prevent emissions to air, soil, and water; use spill containment measures
Appearance: Yellow or orange-yellow crystalline powder
Odor: Odorless
Melting Point: 250–260°C (decomposes)
Solubility in Water: Slightly soluble, better in alkali or in dilute acids
pH (1% solution): 5.0–7.0
Boiling Point: Not applicable (decomposes before boiling)
Density: About 1.68 g/cm³
Flash Point: Not available
Autoignition Temperature: Not determined
Vapor Pressure: Not relevant
Partition Coefficient (Log Pow): −2.8 (estimated)
Stability under Standard Conditions: Stable under recommended storage
Chemical Stability: Stable under normal handling and storage conditions
Possible Hazardous Reactions: None known under usual conditions, but contact with oxidizers may cause reaction
Conditions to Avoid: High temperature, direct sunlight, moisture, strong acids, and bases
Incompatible Materials: Oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia upon heating
Acute Toxicity: Low toxicity, LD50 oral (rat) > 10,000 mg/kg
Chronic Toxicity: No chronic toxicity reported at nutritional/therapeutic levels, excessive intake may risk neurological symptoms by masking B12 deficiency
Eye/Skin Irritation: May cause mild temporary irritation
Respiratory Effects: Dust inhalation can irritate mucous membranes
Sensitization: Not a known skin or respiratory sensitizer at occupational exposure
Mutagenicity/Carcinogenicity: Not classified as mutagenic or carcinogenic
Reproductive Effects: Required for prenatal development, no adverse reproductive effects reported at typical doses
Ecotoxicity: No significant aquatic toxicity expected (based on structure and intended dose)
Persistence and Degradability: Rapidly biodegradable under environmental conditions
Bioaccumulation Potential: Low bioaccumulation hazard due to water solubility and rapid metabolism
Mobility in Soil: Likely dissipates into soil, water quickly due to low absorption to solids
Other Adverse Effects: No significant ozone depletion, bioaccumulation, or endocrine disruption documented
Product Disposal: Dispose in accordance with local, regional, and national laws; treat as non-hazardous laboratory waste unless contamination is known
Container Disposal: Rinse and dispose as ordinary laboratory or industrial chemical waste if not contaminated
Recommended Methods: Incineration or landfill at licensed facility
Precautions: Avoid release of large amounts into environment
UN Number: Not regulated
Proper Shipping Name: Folic Acid
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not applicable
Labels Required: None
Special Precautions: Protect from physical damage, keep dry during transport
Additional Transport Data: May be shipped as foodstuff, supplement, or laboratory material according to carrier requirements
Global Inventory Listings: Listed on China IECSC, US TSCA, EU EINECS, Japan ENCS, Canada DSL
Regulatory Status: Approved as food additive and supplement by food safety authorities such as FDA, EFSA, CFDA under specified limits
Workplace Safety: General chemical workplace rules apply; specific local occupational health standards may reference general dust
Labeling Requirements: Product labeling follows local regulatory guidelines for chemicals and food additives, including batch, purity, and expiration
Restrictions: None for industrial, supplement, or laboratory use; follow food additive regulations for edible products
